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Selenium WHAT IS IT KNOWN AS? Known only as selenium.  It is a trace element found on the periodic table of elements with the abbreviation, Se, and the atomic number 34. HOW DOES IT WORK? Selenium is an antioxidant which regulates important enzymes that protect against oxidized molecules such as low density lipoproteins (LDL). It also inhibits aggregation of small blood components known as platelets which can build up on plaque within the heart arteries and lead to a heart attack.   Selenium is also thought to protect the heart from damage attributed to toxic heavy metals (1). HAS IT BEEN STUDIED IN HEART DISEASE? Selenium supplementation has gained some support for the prevention of coronary heart disease (CHD).  There appears to be an inverse rela- tionship between selenium levels and the incidence of cardiovascular disease.  A reduced selenium level in humans has been associated with an increased risk of heart attack (acute myocardial infarction) (2).  This benefi- cial effect may be a result of the antioxidant properties of selenium.   The deficiency of selenium may also promote the formation of blood clots which may lead to heart attack (3). Whether or not supplementation with seleni- um actually reduces the risk of a cardiovascular event, such as heart attack, has not yet been established in clini- cal studies. In congestive heart failure (CHF), selenium deficiency has been linked to a car- diomyopathy (heart muscle disorder), called Keshan dis- ease.  This disease is endemic to China and affects many children and young women (4).  Selenium defi- ciency has also been linked What is it known as? How does it work? Has it been studied in heart disease? Is it for me? Is it safe? Are there any reported interactions with herbs, supplements or drugs? Are there any interac- tions with laboratory tests? Where can it be found naturally? What is the most appropriate dosage? The lower the level of selenium, the higher the associated risk of heart attack.

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